H. pylori Ag MonlabTest® is a rapid chromatographic immunoassay for the qualitative detection of H. pylori antigens in human feces specimens to aid in the diagnosis of H. pylori infection.
Helicobacter pylori (H. pylori) is a small, spiral-shaped bacterium that is found in the surface of the stomach (epithelial lining) and duodenum (mucous layer). H. pylori causes duodenal ulcers and gastric ulcers. The importance of Helicobacter pylori testing has increased greatly since the strong correlation between the presence of bacteria and confirmed gastrointestinal diseases (stomach and duodenum) like gastritis, peptic ulcer disease and gastric carcinoma. Invasive and non-invasive methods are used to diagnosis H. pylori infection in patients with symptoms of gastrointestinal disease.
The H. pylori Ag MonlabTest® is a qualitative lateral flow immunoassay for the detection of Helicobacter pylori antigen in human feces samples. The membrane is pre-coated with
monoclonal and polyclonal antibodies against H. pylori antigens on the test line region. During testing, the sample reacts with the particle coated with anti-H. pylori antibodies which was pre-dried on the test strip. The mixture moves upward on the membrane by capillary action. In the case of a positive result the specific antibodies present on the membrane will react with the mixture conjugate and generate a coloured line. A green coloured band always appears in the control line and serves as verification that sufficient volume was added, that proper flow was obtained and as an internal control for the reagents.